Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.47 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568958 | 1.00 | LTA4H (0.52) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL11762365 | 0.86 | LNPEP (0.54) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL11762373 | 0.86 | LNPEP (0.54) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL30052981 | 0.85 | LTA4H (0.66) | LTA4HMMEBACE1 | |
| SCHEMBL11568405 | 0.82 | MME (0.50) | LTA4HMME | |
| SCHEMBL11568394 | 0.82 | MME (0.50) | LTA4HMME | |
| SCHEMBL32681297 | 0.81 | FOLH1 (0.60) | LTA4HMMEACEOPRD1BACE1 | |
| Hydrochloric Acid SCHEMBL31321913 | 0.80 | ERAP2 (0.56) | LTA4HMMEACECPA1ACE2 | |
| SCHEMBL8332105 | 0.79 | FOLH1 (0.58) | LTA4HOPRD1BACE1 | |
| SCHEMBL8332107 | 0.79 | FOLH1 (0.58) | LTA4HOPRD1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146614-A | TREATMENT OF SCHIZOPHRENIA | STATE OF MICHIGAN (US) | 1979-03-27 | — | — | US | disclosed |