Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.44 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11566101 | 0.95 | SIGMAR1 (0.46) | DRD2DRD3SIGMAR1NPFFR1NPFFR2 | |
| SCHEMBL11564641 | 0.87 | NPFFR1 (0.53) | SIGMAR1NPFFR1NPFFR2 | |
| SCHEMBL11568672 | 0.84 | NPFFR1 (0.44) | DRD2DRD3SIGMAR1NPFFR1NPFFR2 | |
| SCHEMBL9148987 | 0.84 | NPFFR1 (0.61) | DRD2SIGMAR1NPFFR1NPFFR2KCNH2 | |
| Hydrochloric Acid SCHEMBL11565432 | 0.83 | NPFFR1 (0.60) | DRD2SIGMAR1NPFFR1NPFFR2KCNH2 | |
| SCHEMBL11566633 | 0.82 | NPFFR1 (0.45) | SIGMAR1NPFFR1NPFFR2OPRM1 | |
| SCHEMBL3167579 | 0.81 | NPFFR1 (0.60) | SIGMAR1NPFFR1NPFFR2OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL11565355 | 0.80 | NPFFR1 (0.58) | SIGMAR1NPFFR1NPFFR2OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL27922841 | 0.80 | NPFFR1 (0.58) | SIGMAR1NPFFR1NPFFR2OPRM1OPRL1 | |
| SCHEMBL28838474 | 0.80 | NPFFR1 (0.39) | NPFFR1NPFFR2KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179569-A | ANALGESIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-12-18 | — | — | US | disclosed |