Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 7/20 | 0.55 |
| ▸ | PPARG | P37231 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PPARD | Q03181 | 2/20 | 0.54 |
| ▸ | FABP2 | P12104 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.53 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.53 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.53 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.53 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.53 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.53 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.53 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.53 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.53 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.53 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.53 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11569457 | 1.00 | MAPT (0.58) | MAPTLMNAPPARAPPARGALDH1A1 | |
| SCHEMBL11568796 | 0.91 | MAPT (0.65) | MAPTLMNAPPARAPPARGALDH1A1 | |
| SCHEMBL11568800 | 0.91 | MAPT (0.65) | MAPTLMNAPPARAPPARGALDH1A1 | |
| SCHEMBL11569595 | 0.90 | MAPT (0.58) | MAPTLMNAPPARAPPARGALDH1A1 | |
| SCHEMBL11569596 | 0.90 | MAPT (0.58) | MAPTLMNAPPARAPPARGALDH1A1 | |
| SCHEMBL11569152 | 0.90 | PPARA (0.67) | MAPTPPARAPPARGALDH1A1PPARD | |
| SCHEMBL11569149 | 0.90 | PPARA (0.67) | MAPTPPARAPPARGALDH1A1PPARD | |
| SCHEMBL11573795 | 0.88 | MAPT (0.55) | MAPTLMNAPPARAALDH1A1NDUFS8 | |
| SCHEMBL11573799 | 0.88 | MAPT (0.55) | MAPTLMNAPPARAALDH1A1NDUFS8 | |
| SCHEMBL11569070 | 0.85 | PYGL (0.58) | MAPTPPARAPPARGALDH1A1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151303-A | Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions | BOEHRINGER MANNHEIM GMBH (DE) | 1979-04-24 | — | — | US | disclosed |