SCHEMBL11569070

SCHEMBL11569070

CC(C)(Oc1ccc(CCNC(=O)C=Cc2ccc(Cl)c(Cl)c2)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PYGL P06737 11/20 0.58
ALDH1A1 P00352 3/20 0.55
PPARA Q07869 2/20 0.55
FABP2 P12104 1/20 0.55
PPARG P37231 1/20 0.55
PPARD Q03181 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
MAPT P10636 2/20 0.50
HPGD P15428 1/20 0.50
NLRP3 Q96P20 1/20 0.50
KDM4E B2RXH2 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11569069 1.00 PYGL (0.58) PYGLALDH1A1PPARAFABP2PPARG
SCHEMBL11573845 0.93 ALDH1A1 (0.56) PYGLALDH1A1PPARAFABP2PPARG
SCHEMBL11573847 0.93 ALDH1A1 (0.56) PYGLALDH1A1PPARAFABP2PPARG
SCHEMBL11569149 0.89 PPARA (0.67) ALDH1A1PPARAFABP2PPARGPPARD
SCHEMBL11569152 0.89 PPARA (0.67) ALDH1A1PPARAFABP2PPARGPPARD
SCHEMBL11571057 0.88 PYGL (0.54) PYGLPPARAMAPT
SCHEMBL11571061 0.88 PYGL (0.54) PYGLPPARAMAPT
SCHEMBL11568796 0.85 MAPT (0.65) ALDH1A1PPARAFABP2PPARGPPARD
SCHEMBL11569457 0.85 MAPT (0.58) ALDH1A1PPARAFABP2PPARGPPARD
SCHEMBL11569464 0.85 MAPT (0.58) ALDH1A1PPARAFABP2PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4151303-A Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions BOEHRINGER MANNHEIM GMBH (DE) 1979-04-24 US claimed
US-4151303-A Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions BOEHRINGER MANNHEIM GMBH (DE) 1979-04-24 US disclosed