Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805609 | 0.78 | MTNR1A (0.42) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL6489465 | 0.78 | MTNR1A (0.42) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL6489470 | 0.78 | MTNR1A (0.42) | KMT2AMEN1SMN1; SMN2HTTLMNA | |
| SCHEMBL11571322 | 0.77 | CYP2C19 (0.50) | HPGDSMN1; SMN2LMNAMMP1MMP2 | |
| SCHEMBL515915 | 0.76 | CA12 (0.54) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL515914 | 0.76 | CA12 (0.54) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8373371 | 0.76 | CA12 (0.54) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4754929 | 0.74 | CA12 (0.53) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| Water SCHEMBL4754935 | 0.74 | CA12 (0.53) | KMT2AMEN1MAPTHPGDSMN1; SMN2 | |
| Water SCHEMBL4754936 | 0.74 | CA12 (0.53) | KMT2AMEN1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153688-A | N-TRIFLUOROACETYL-ALANYL OR LYSYL-ALANYL OR LYSYL-ANILIDE, REVERSIBLE ELASTASE ENZYME INHIBITORS | DELALANDE S.A. (FR) | 1979-05-08 | — | — | US | disclosed |