SCHEMBL515915

SCHEMBL515915

C[C@H](Nc1ccc([N+](=O)[O-])cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP14 P50281 1/20 0.54
MEN1 O00255 6/20 0.53
KMT2A Q03164 6/20 0.53
HPGD P15428 1/20 0.53
ALOX12 P18054 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
GAA P10253 2/20 0.53
ALDH1A1 P00352 3/20 0.52
RECQL P46063 2/20 0.52
HSD17B10 Q99714 1/20 0.52
HTT P42858 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 3/20 0.49
RAB9A P51151 2/20 0.49
POLB P06746 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373371 1.00 CA12 (0.54) CA12CA1MMP2MMP9MMP8
SCHEMBL515914 1.00 CA12 (0.54) CA12CA1MMP2MMP9MMP8
Water SCHEMBL4754936 0.98 CA12 (0.53) CA12CA1MMP2MMP9MMP8
Water SCHEMBL4754935 0.98 CA12 (0.53) CA12CA1MMP2MMP9MMP8
Hydrochloric Acid SCHEMBL4754929 0.98 CA12 (0.53) CA12CA1MMP2MMP9MMP8
Glycine SCHEMBL8137571 0.91 MEN1 (0.47) CA12CA1MMP2MMP9MMP8
SCHEMBL11906704 0.84 ALDH1A1 (0.44) CA12CA1MMP2MMP9MMP8
Benzoic Acid SCHEMBL11907514 0.84 KMT2A (0.49) CA12CA1MMP2MMP9MMP8
Hydrochloric Acid SCHEMBL5967288 0.83 CA12 (0.51) CA12CA1MMP2MMP9MMP8
SCHEMBL6254462 0.83 MMP9 (0.58) CA12CA1MMP2MMP9MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4117732-A1 INTERLEUKIN-2 POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF Ambrx, Inc. (US) 2023-01-18 EP claimed
CN-109554437-A A kind of dual wavelength microbial biochemical reaction dynamic interpretation detection method 湖南长沙天地人生物科技有限公司 2019-04-02 CN claimed
CN-108779150-A The Preparation Method And Their Intermediate of Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-4Aph(Hor)-D-4Aph(Cbm)-Leu-Lys(iPr)-Pro-D-Ala-NH2 费森尤斯卡比依普莎姆责任有限公司 2018-11-09 CN claimed
CN-103149351-A Synthesis and application of envelope antigen universal for pyrethriods pesticide UNIV JIANGNAN 2013-06-12 CN claimed
US-20110178151-A1 COMPOUNDS AND METHODS OF TREATING OBESITY YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW (IL) 2011-07-21 US claimed
EP-2262763-A2 COMPOUNDS AND METHODS OF TREATING OBESITY Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2010-12-22 EP claimed
WO-2009109973-A2 COMPOUNDS AND METHODS OF TREATING OBESITY YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2009-09-11 WO claimed
US-5565328-A COLORIMETRIC ANALYSIS WITH FLUOROMETRIC READER USING SUITABLE FLUOROPHORE DADE INTERNATIONAL INC. (US) 1996-10-15 US claimed
EP-4743578-A2 THERAPY FOR ALPHA-1 ANTITRYPSIN DEFICIENCY Precigen, Inc. (US) 2026-05-20 EP disclosed
EP-4598568-A1 PRAME IMMUNOGENIC PEPTIDES, BINDING PROTEINS RECOGNIZING PRAME IMMUNOGENIC PEPTIDES, AND USES THEREOF Tscan Therapeutics, Inc. (US) 2025-08-13 EP disclosed
WO-2025147774-A1 COMPOSITIONS TARGETING BRADYKININ RECEPTOR B1 FOR MEDICAL IMAGING AND TREATMENT OF CANCER AND OTHER DISORDERS ALPHA-9 ONCOLOGY INC. (CA) 2025-07-17 WO disclosed
WO-2025097034-A1 METHODS FOR MANUFACTURE OF ENGINEERED T CELLS FROM WHOLE BLOOD SAMPLES Kyverna Therapeutics, Inc. (US) 2025-05-08 WO disclosed
CN-113396218-B Engineered transaminase polypeptides 科德克希思公司 2025-02-18 CN disclosed
US-12226476-B2 Helper epitope peptide and application thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2025-02-18 US disclosed
EP-0416033-A1 MACROCYCLIC CHELATES AND METHODS OF USE THEREOF. US COMMERCE (US) 1991-03-13 EP disclosed
US-4923985-A Process for synthesizing macrocyclic chelates THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 1990-05-08 US disclosed
WO-1989011475-A1 MACROCYCLIC CHELATES AND METHODS OF USE THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH (US) 1989-11-30 WO disclosed
US-4818748-A HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1989-04-04 US disclosed
EP-0236874-A2 Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes BAYER AG (DE) 1987-09-16 EP disclosed
EP-0018825-A1 A process for the identification of bacteria and a kit of reagents for use in this process NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1980-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110178151-A1 COMPOUNDS AND METHODS OF TREATING OBESITY GPR119, FABP4, LIPC CA12 3310/4885CA1 1920/4885MMP2 2168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.