Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571254 | 1.00 | HRH4 (0.45) | HRH4HRH3LMNAFFAR1MAPT | |
| SCHEMBL11571424 | 1.00 | HRH4 (0.45) | HRH4HRH3LMNAFFAR1MAPT | |
| SCHEMBL11596869 | 0.93 | LMNA (0.51) | HRH4HRH3LMNAFFAR1NPC1 | |
| SCHEMBL11569838 | 0.88 | HRH4 (0.46) | HRH4HRH3LMNAFFAR1 | |
| SCHEMBL11593465 | 0.85 | HCAR2 (0.43) | HRH4HRH3FFAR1NPC1RAB9A | |
| SCHEMBL1263885 | 0.85 | HRH4 (0.44) | HRH4HRH3LMNAFFAR1NAAA | |
| SCHEMBL2310305 | 0.85 | HRH4 (0.44) | HRH4HRH3LMNAFFAR1NAAA | |
| SCHEMBL1263483 | 0.85 | HRH4 (0.44) | HRH4HRH3LMNAFFAR1NAAA | |
| SCHEMBL21681727 | 0.84 | LMNA (0.62) | LMNAFFAR1MAPTRXFP1NPC1 | |
| SCHEMBL21681726 | 0.84 | LMNA (0.62) | LMNAFFAR1MAPTRXFP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175544-A | X-RAYS OF BODY FOR MEDICAL DIAGNOSIS | Lafayette Pharmacal Inc. (US) | 1979-11-27 | — | — | US | disclosed |