SCHEMBL11569838

SCHEMBL11569838

O=C(OCCCCCc1ccc(I)cc1)OCCCCCc1ccc(I)cc1

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.46
HRH3 Q9Y5N1 1/20 0.46
LMNA P02545 1/20 0.42
FFAR1 O14842 1/20 0.41
SPHK2 Q9NRA0 3/20 0.38
SPHK1 Q9NYA1 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11596868 0.93 HRH4 (0.51) HRH4HRH3LMNAFFAR1
SCHEMBL11571254 0.88 HRH4 (0.45) HRH4HRH3LMNAFFAR1
SCHEMBL11569840 0.88 HRH4 (0.45) HRH4HRH3LMNAFFAR1
SCHEMBL11571424 0.88 HRH4 (0.45) HRH4HRH3LMNAFFAR1
SCHEMBL2310305 0.86 HRH4 (0.44) HRH4HRH3LMNAFFAR1
SCHEMBL1263483 0.86 HRH4 (0.44) HRH4HRH3LMNAFFAR1
SCHEMBL1263885 0.86 HRH4 (0.44) HRH4HRH3LMNAFFAR1
SCHEMBL11593462 0.85 TYR (0.41) HRH4HRH3
SCHEMBL2308337 0.84 HRH4 (0.45) HRH4HRH3LMNAFFAR1
SCHEMBL1791114 0.82 LMNA (0.42) LMNAFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4175544-A X-RAYS OF BODY FOR MEDICAL DIAGNOSIS Lafayette Pharmacal Inc. (US) 1979-11-27 US disclosed