SCHEMBL1157

SCHEMBL1157

O=Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.61
FBP1 P09467 2/20 0.59
NPC1 O15118 1/20 0.55
MAPT P10636 1/20 0.55
RAB9A P51151 1/20 0.55
ALDH1A1 P00352 3/20 0.53
ACHE P22303 1/20 0.52
HSD17B10 Q99714 1/20 0.52
PTGS2 P35354 2/20 0.52
PTGS1 P23219 1/20 0.52
CYP19A1 P11511 1/20 0.52
AMY1A P0DUB6 1/20 0.52
LMNA P02545 1/20 0.50
METAP1 P53582 1/20 0.48
GRIN2D O15399 1/20 0.48
GRIN3B O60391 1/20 0.48
GRIN1 Q05586 1/20 0.48
GRIN2A Q12879 1/20 0.48
GRIN2B Q13224 1/20 0.48
GRIN2C Q14957 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29016137 0.98 APP (0.59) APPFBP1NPC1MAPTRAB9A
Ammonia Solution, Strong SCHEMBL28564961 0.98 APP (0.59) APPFBP1NPC1MAPTRAB9A
SCHEMBL28981615 0.98 APP (0.59) APPFBP1NPC1MAPTRAB9A
Hydrazine SCHEMBL9322622 0.95 APP (0.57) APPFBP1NPC1MAPTRAB9A
SCHEMBL5514209 0.93 APP (0.67) APPFBP1NPC1MAPTRAB9A
SCHEMBL1580201 0.93 ALDH1A1 (0.56) APPFBP1NPC1MAPTRAB9A
SCHEMBL5514207 0.93 APP (0.67) APPFBP1NPC1MAPTRAB9A
Benzaldehyde SCHEMBL4022100 0.91 ALDH1A1 (0.60) APPFBP1NPC1MAPTRAB9A
SCHEMBL9613713 0.91 APP (0.53) APPFBP1NPC1MAPTRAB9A
SCHEMBL8068948 0.89 ACHE (0.72) APPFBP1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 22214 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080349-A High molecular weight polyacetal-siloxane copolymer and preparation method thereof 2026-05-26 CN claimed
US-12636642-B2 Porphyrin-based metal coordination conjugated polymer, preparation method therefor, and application thereof in photocatalytic degradation of organic pollutants SOOCHOW UNIVERSITY (CN) 2026-05-26 US claimed
CN-122060375-A Corrosion-resistant fireproof explosion-proof material, preparation method thereof and application thereof in electric power tunnel 南昌泰事达电气科技有限公司 2026-05-19 CN claimed
CN-122036618-A Synthesis process of 4-aryl imidazole 浙江工业大学 2026-05-15 CN claimed
CN-117402106-B Multidentate organic ligand containing triphenylamine-terpyridine structure, metal supermolecular polymer, polymer film and preparation method 吉林大学 2026-05-12 CN claimed
US-12624144-B2 Method for preparing hollow covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2026-05-12 US claimed
US-20260117040-A1 DEPOLYMERIZATION OF AMINATED ALL-CARBON POLYMER BACKBONES THROUGH AZA-COPE REARRANGEMENTS UNIV NORTH CAROLINA CHAPEL HILL (US) 2026-04-30 US claimed
CN-121574130-A Synthesis method of pyrazolo [1,2-b ] phthalazine-5, 10-dione derivative as drug intermediate and catalytic system for synthesis 南京苏亦欣医药科技有限公司 2026-02-27 CN claimed
US-12503449-B2 Methods of preparing chiral benzodiazepinone derivatives IMMUNOME, INC. (US) 2025-12-23 US claimed
US-20250346565-A1 METHODS OF PREPARING CHIRAL BENZODIAZEPINONE DERIVATIVES AYALA PHARMACEUTICALS INC. 2025-11-13 US claimed
US-3978049-A Process for the preparation of hydrazine compounds PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-31 US claimed
US-3974137-A ANTIBACTERIAL, ALDEHYDE BLOCKING AGENT BRISTOL-MYERS COMPANY (US) 1976-08-10 US claimed
US-3972876-A Process for the preparation of symmetrical and unsymmetrical azines and mixtures thereof PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US claimed
US-3972878-A Method for preparing azines and hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US claimed
US-3959262-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-05-25 US claimed
US-3956282-A Method for preparing azines TELLIER PIERRE 1976-05-11 US claimed
US-3951964-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-20 US claimed
US-3948902-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-04-06 US claimed
US-3943132-A Process for the preparation of hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed
US-3943152-A Method for preparing azines PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-03-09 US claimed