Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.71 |
| ▸ | AR | P10275 | 5/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.71 |
| ▸ | NR3C1 | P04150 | 13/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.70 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253096 | 0.90 | PGR (0.76) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL4228192 | 0.90 | NR3C1 (0.77) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL11357530 | 0.90 | PGR (0.73) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL5535751 | 0.90 | PGR (0.82) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL2181440 | 0.90 | PGR (0.82) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL192155 | 0.90 | PGR (0.82) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL17748176 | 0.90 | PGR (0.82) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL2554938 | 0.90 | PGR (0.82) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL6842246 | 0.90 | PGR (0.82) | PGRARADORA3CHRM1ADRA1A | |
| SCHEMBL7901488 | 0.90 | PGR (0.82) | PGRARADORA3CHRM1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004741-A2 | Thio etianic acid derivatives, their preparation and pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1979-10-17 | — | — | EP | disclosed |