Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574115 | 0.87 | KDM4E (0.57) | ALDH1A1HSD17B10KDM4EGLAKMT2A | |
| SCHEMBL10954896 | 0.83 | KDM4E (0.59) | ALDH1A1HSD17B10KDM4EGLAKMT2A | |
| SCHEMBL11572282 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4EGLAADRB2 | |
| SCHEMBL11572952 | 0.81 | KDM4E (0.51) | ALDH1A1HSD17B10KDM4EGLAKMT2A | |
| SCHEMBL7628551 | 0.78 | KDM4E (0.64) | ALDH1A1HSD17B10KDM4EGLAKMT2A | |
| SCHEMBL11573064 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HSD17B10KDM4EGLAKMT2A | |
| SCHEMBL11572479 | 0.77 | KDM4E (0.56) | ALDH1A1HSD17B10KDM4EGLAKMT2A | |
| SCHEMBL11573154 | 0.77 | KDM4E (0.52) | ALDH1A1HSD17B10KDM4EGLAKMT2A | |
| SCHEMBL6513522 | 0.77 | KDM4E (0.68) | ALDH1A1HSD17B10KDM4EGLAKMT2A | |
| SCHEMBL11570152 | 0.76 | KDM4E (0.57) | ALDH1A1HSD17B10KDM4EGLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152114-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1979-05-01 | — | — | US | disclosed |
| US-4099909-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1978-07-11 | — | — | US | disclosed |
| US-3963431-A | POLYESTER | CIBA-GEIGY AG (CH) | 1976-06-15 | — | — | US | disclosed |