Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572479 | 0.87 | KDM4E (0.56) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11571260 | 0.87 | KDM4E (0.52) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11572662 | 0.84 | KDM4E (0.49) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11574037 | 0.83 | ALDH1A1 (0.52) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL10954896 | 0.82 | KDM4E (0.59) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11649769 | 0.80 | KDM4E (0.47) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11570124 | 0.78 | KDM4E (0.46) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL11674847 | 0.77 | MAPT (0.47) | KDM4EALDH1A1HSD17B10KMT2AATM | |
| SCHEMBL11570245 | 0.77 | ALDH1A1 (0.56) | KDM4EGLAALDH1A1HSD17B10KMT2A | |
| SCHEMBL7628551 | 0.77 | KDM4E (0.64) | KDM4EGLAALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152114-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1979-05-01 | — | — | US | disclosed |
| US-4099909-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1978-07-11 | — | — | US | disclosed |
| US-3963431-A | POLYESTER | CIBA-GEIGY AG (CH) | 1976-06-15 | — | — | US | disclosed |