Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17896872 | 0.81 | HTT (0.71) | LMNAHTTALDH1A1ATAD2CECR2 | |
| SCHEMBL20792617 | 0.76 | LMNA (0.39) | LMNAHTTKMT2AALDH1A1RAB9A | |
| SCHEMBL18626563 | 0.76 | HTT (0.66) | LMNAHTTKMT2AALDH1A1ATAD2 | |
| SCHEMBL20666231 | 0.75 | LMNA (0.64) | LMNAHTTKMT2AALDH1A1NQO2 | |
| SCHEMBL11511345 | 0.75 | LMNA (0.58) | LMNAHTTALDH1A1NQO2NPC1 | |
| SCHEMBL11513986 | 0.74 | HTT (0.60) | LMNAHTTKMT2AALDH1A1NQO2 | |
| Nefiracetam SCHEMBL135856 | 0.73 | HTT (0.66) | LMNAHTTKMT2AALDH1A1ATAD2 | |
| SCHEMBL2998036 | 0.72 | HTT (0.58) | LMNAHTTALDH1A1RAB9ANPC1 | |
| SCHEMBL20666108 | 0.71 | LMNA (0.59) | LMNAHTTKMT2AALDH1A1ATAD2 | |
| SCHEMBL21988615 | 0.71 | LMNA (0.58) | LMNAHTTKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003029-A2 | New 2-oxo-1-pyrrolidine acetic acid derivatives, process for their preparation, medicaments containing them and process for their preparation | Troponwerke GmbH & Co. KG (DE) | 1979-07-25 | — | — | EP | disclosed |