Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513986 | 0.83 | HTT (0.60) | LMNAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11570308 | 0.75 | LMNA (0.56) | LMNAHTTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL10813610 | 0.73 | SMN1; SMN2 (0.70) | LMNAHTTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL20666231 | 0.73 | LMNA (0.64) | LMNAHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL11391291 | 0.72 | HTT (1.00) | LMNAHTTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL24661545 | 0.72 | SMN1; SMN2 (0.62) | LMNAHTTSMN1; SMN2NPC1TDP1 | |
| SCHEMBL11841853 | 0.72 | SMN1; SMN2 (0.62) | LMNASMN1; SMN2NPC1TDP1 | |
| SCHEMBL11512972 | 0.71 | LMNA (0.56) | LMNAHTTSMN1; SMN2L3MBTL1NQO2 | |
| SCHEMBL11512976 | 0.71 | LMNA (0.56) | LMNAHTTSMN1; SMN2L3MBTL1NQO2 | |
| SCHEMBL11251922 | 0.71 | KMT2A (0.48) | LMNAHTTSMN1; SMN2ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |