Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL249850 | 0.76 | TSHR (0.39) | TSHRCYP2D6CYP2C19HIF1ASLC22A6 | |
| SCHEMBL8372729 | 0.76 | TSHR (0.39) | TSHRCYP2D6CYP2C19HIF1ASLC22A6 | |
| SCHEMBL28746032 | 0.76 | CHRM1 (0.39) | TSHRADRA1ATDP1CHRM1ALDH1A1 | |
| SCHEMBL20711453 | 0.75 | SLC22A6 (0.41) | TSHRCYP2D6CYP2C19HIF1ASLC22A6 | |
| SCHEMBL1572820 | 0.75 | SLC22A6 (0.41) | TSHRCYP2D6CYP2C19HIF1ASLC22A6 | |
| SCHEMBL23913764 | 0.75 | SLC22A6 (0.41) | TSHRCYP2D6CYP2C19HIF1ASLC22A6 | |
| SCHEMBL5740045 | 0.74 | ADRA1A (0.44) | TSHRCYP2D6CYP2C19HIF1ASLC22A6 | |
| SCHEMBL5150731 | 0.74 | SLC22A6 (0.36) | SLC22A6CACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL1300987 | 0.74 | TSHR (0.39) | TSHRCYP2D6CYP2C19HIF1ASLC22A6 | |
| Ammonia Solution, Strong SCHEMBL8858462 | 0.74 | TDP1 (0.40) | TSHRCYP2D6CYP2C19HIF1ASLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001840-A2 | Stabilising mixtures, process for stabilising synthetic materials against light with these mixtures and synthetic materials so stabilised | CIBA-GEIGY AG (CH) | 1979-05-16 | — | — | EP | disclosed |