Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570653 | 0.91 | ALDH1A1 (0.38) | ALDH1A1FOLH1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL11571147 | 0.80 | CTSK (0.42) | ALDH1A1FOLH1CTSK | |
| SCHEMBL11570912 | 0.80 | CTSK (0.42) | ALDH1A1FOLH1CTSK | |
| SCHEMBL11571263 | 0.80 | FOLH1 (0.43) | ALDH1A1FOLH1CTSKGPR84 | |
| SCHEMBL11570170 | 0.80 | FOLH1 (0.43) | ALDH1A1FOLH1CTSKGPR84 | |
| SCHEMBL11572453 | 0.80 | FOLH1 (0.43) | ALDH1A1FOLH1CTSKGPR84 | |
| SCHEMBL11569699 | 0.79 | S1PR2 (0.46) | ALDH1A1 | |
| SCHEMBL11571422 | 0.79 | CTSK (0.43) | ALDH1A1FOLH1CTSK | |
| SCHEMBL11571505 | 0.78 | FOLH1 (0.41) | ALDH1A1FOLH1CTSKCNR2GPR84 | |
| SCHEMBL9015763 | 0.75 | SLC2A1 (0.39) | FOLH1CTSKGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022814-A | Iodine containing organic carbonates for use as radiographic agents | LAFAYETTE PHARMACAL, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4175544-A | X-RAYS OF BODY FOR MEDICAL DIAGNOSIS | Lafayette Pharmacal Inc. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4022814-A | Iodine containing organic carbonates for use as radiographic agents | LAFAYETTE PHARMACAL, INC. (US) | 1977-05-10 | — | — | US | disclosed |