Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12017964 | 0.79 | SMN1; SMN2 (0.67) | KMT2AMAPK1MEN1ALDH1A1ADRA2C | |
| SCHEMBL12970664 | 0.75 | MEN1 (0.52) | KMT2AMAPK1MEN1ALDH1A1ADRA2C | |
| SCHEMBL11654455 | 0.74 | ALDH1A1 (0.46) | KMT2AMAPK1MEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11570666 | 0.74 | ADRA2C (0.52) | KMT2AMAPK1MEN1ALDH1A1ADRA2C | |
| SCHEMBL17518984 | 0.74 | KMT2A (0.55) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2446173 | 0.71 | MAPT (0.55) | KMT2AMAPK1ALDH1A1ADRA2CLMNA | |
| SCHEMBL8013861 | 0.71 | KCNH2 (0.56) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8864726 | 0.71 | ALDH1A1 (0.57) | KMT2AMAPK1MEN1ALDH1A1LMNA | |
| SCHEMBL5359155 | 0.71 | ALDH1A1 (0.53) | KMT2AMAPK1MEN1ALDH1A1ADRA2C | |
| SCHEMBL6992085 | 0.71 | TSHR (0.54) | KMT2AMAPK1MEN1ALDH1A1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179435-A | SULPHONIC ACID-FREE | CIBA-GEIGY CORPORATION (US) | 1979-12-18 | — | — | US | disclosed |