Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 7/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11346088 | 0.97 | SIGMAR1 (0.37) | BCL2A1SIGMAR1ALDH1A1RAB9AHTT | |
| SCHEMBL11456934 | 0.91 | SMN1; SMN2 (0.34) | ALDH1A1RAB9AHTTMEN1KMT2A | |
| SCHEMBL11341247 | 0.88 | NPC1 (0.36) | ALDH1A1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11446841 | 0.87 | SIGMAR1 (0.40) | BCL2A1SIGMAR1ALDH1A1RAB9AHTT | |
| SCHEMBL11465734 | 0.86 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1RAB9AHTTMEN1 | |
| Fumaric Acid SCHEMBL11447589 | 0.85 | ALDH1A1 (0.37) | BCL2A1SIGMAR1ALDH1A1RAB9AHTT | |
| SCHEMBL11454495 | 0.83 | GAA (0.36) | SIGMAR1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL11332175 | 0.83 | SIGMAR1 (0.42) | BCL2A1SIGMAR1ALDH1A1RAB9AHTT | |
| SCHEMBL11330691 | 0.83 | SIGMAR1 (0.38) | SIGMAR1ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL11346058 | 0.83 | MEN1 (0.41) | SIGMAR1ALDH1A1RAB9AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | claimed |
| US-4159340-A | N-(2-Aminocyclopentyl)-N-acylanilides as CNS anti-depressants | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |