Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159951 | 0.80 | CYP19A1 (0.44) | CYP19A1ELANEMAOBACHEKDM4E | |
| SCHEMBL12240335 | 0.78 | ACHE (0.42) | CYP19A1ELANEMAOBACHEKDM4E | |
| SCHEMBL12240339 | 0.78 | ACHE (0.42) | CYP19A1ELANEMAOBACHEKDM4E | |
| SCHEMBL67625 | 0.74 | ACHE (0.44) | CYP19A1ELANEMAOBACHEKDM4E | |
| SCHEMBL10360797 | 0.73 | MAOB (0.48) | CYP19A1ELANEMAOBKDM4EMEN1 | |
| SCHEMBL11574837 | 0.70 | CYP19A1 (0.38) | CYP19A1ELANEMAOBKDM4EMEN1 | |
| SCHEMBL69687 | 0.69 | KDM4E (0.40) | CYP19A1ELANEMAOBACHEKDM4E | |
| SCHEMBL12993270 | 0.69 | GAA (0.39) | CYP19A1MAOBKDM4EMEN1KMT2A | |
| SCHEMBL11572962 | 0.69 | CYP19A1 (0.37) | CYP19A1ELANEMAOBKDM4EMEN1 | |
| SCHEMBL11201233 | 0.69 | ELANE (0.39) | CYP19A1ELANEMAOBACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134813-A | THIOCHROMANONES, AMINE | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-16 | — | — | US | disclosed |