Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207304 | 0.82 | KMT2A (0.37) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5159951 | 0.72 | CYP19A1 (0.44) | ELANECYP19A1KDM4ELMNAHTT | |
| SCHEMBL11205372 | 0.71 | TP53 (0.36) | CYP19A1LMNAHTTNPSR1MEN1 | |
| SCHEMBL67625 | 0.69 | ACHE (0.44) | ELANECYP19A1KDM4ELMNAHTT | |
| SCHEMBL11570849 | 0.69 | CYP19A1 (0.42) | ELANECYP19A1KDM4ELMNAHTT | |
| SCHEMBL69687 | 0.67 | KDM4E (0.40) | ELANECYP19A1KDM4ELMNAHTT | |
| SCHEMBL12240339 | 0.66 | ACHE (0.42) | ELANECYP19A1KDM4ELMNAHTT | |
| SCHEMBL12240335 | 0.66 | ACHE (0.42) | ELANECYP19A1KDM4ELMNAHTT | |
| SCHEMBL10360797 | 0.65 | MAOB (0.48) | ELANECYP19A1KDM4EHTTMEN1 | |
| SCHEMBL11402204 | 0.64 | KMT2A (0.34) | KDM4ELMNANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091041-A2 | Vinylogous carboxamides, process for preparing them and medicines containing these compounds | Dr. Karl Thomae GmbH (DE) | 1983-10-12 | — | — | EP | disclosed |