Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570937 | 0.91 | CTSK (0.40) | CTSKCSNK1ECTSBCTSLPPARG | |
| SCHEMBL11570563 | 0.85 | PRKCA (0.38) | CTSKCTSBCTSLPPARGALDH1A1 | |
| SCHEMBL1837115 | 0.85 | CTSK (0.53) | CTSKCSNK1ECTSBCTSLALDH1A1 | |
| SCHEMBL1839268 | 0.85 | CTSK (0.53) | CTSKCSNK1ECTSBCTSLALDH1A1 | |
| SCHEMBL1841343 | 0.85 | CTSK (0.53) | CTSKCSNK1ECTSBCTSLALDH1A1 | |
| SCHEMBL11571147 | 0.84 | CTSK (0.42) | CTSKCSNK1ECTSBCTSLPPARA | |
| SCHEMBL11570912 | 0.84 | CTSK (0.42) | CTSKCSNK1ECTSBCTSLPPARA | |
| SCHEMBL1837041 | 0.84 | CTSK (0.54) | CTSKCSNK1ECTSBCTSLALDH1A1 | |
| SCHEMBL16067620 | 0.84 | CTSK (0.42) | CTSKCTSBCTSLPPARGFOLH1 | |
| SCHEMBL11571422 | 0.83 | CTSK (0.43) | CTSKCSNK1ECTSBCTSLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022814-A | Iodine containing organic carbonates for use as radiographic agents | LAFAYETTE PHARMACAL, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4175544-A | X-RAYS OF BODY FOR MEDICAL DIAGNOSIS | Lafayette Pharmacal Inc. (US) | 1979-11-27 | — | — | US | disclosed |
| US-4022814-A | Iodine containing organic carbonates for use as radiographic agents | LAFAYETTE PHARMACAL, INC. (US) | 1977-05-10 | — | — | US | disclosed |