Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11327541 | 1.00 | DGKA (0.56) | DGKADNM1MAPTHTTPAM | |
| Bromide SCHEMBL11326341 | 1.00 | DGKA (0.56) | DGKADNM1MAPTHTTPAM | |
| Bromide SCHEMBL9780261 | 0.88 | DGKA (0.65) | DGKADNM1MAPTHTTPAM | |
| Bromide SCHEMBL11577762 | 0.88 | DGKA (0.65) | DGKADNM1MAPTHTTPAM | |
| Bromide SCHEMBL10492800 | 0.88 | DGKA (0.65) | DGKADNM1MAPTHTTPAM | |
| Bromide SCHEMBL11579096 | 0.88 | DGKA (0.65) | DGKADNM1MAPTHTTPAM | |
| SCHEMBL8467040 | 0.88 | MAPT (0.53) | DGKADNM1MAPTHTTPAM | |
| SCHEMBL4201697 | 0.86 | DGKA (0.67) | DGKADNM1MAPTHTTPAM | |
| Bromide SCHEMBL11329023 | 0.86 | DGKA (0.56) | DGKADNM1MAPTPAMTSHR | |
| SCHEMBL4191351 | 0.86 | DGKA (0.67) | DGKADNM1MAPTHTTPAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004686-A2 | Anti-ulcer composition | THE PROCTER & GAMBLE COMPANY (US) | 1979-10-17 | — | — | EP | disclosed |