Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PAM | P19021 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10492800 | 1.00 | DGKA (0.65) | DGKADNM1MAPTPAMHTT | |
| Bromide SCHEMBL11579096 | 1.00 | DGKA (0.65) | DGKADNM1MAPTPAMHTT | |
| Hydrochloric Acid SCHEMBL3462945 | 0.97 | DGKA (0.65) | DGKADNM1MAPTPAMHTT | |
| Hydrochloric Acid SCHEMBL9780397 | 0.97 | DGKA (0.65) | DGKADNM1MAPTPAMHTT | |
| Iodide SCHEMBL9780493 | 0.97 | DGKA (0.65) | DGKADNM1MAPTPAMHTT | |
| SCHEMBL377473 | 0.95 | DGKA (0.71) | DGKADNM1MAPTPAMALDH1A1 | |
| SCHEMBL1056065 | 0.95 | DGKA (0.71) | DGKADNM1MAPTPAMALDH1A1 | |
| SCHEMBL1052058 | 0.95 | DGKA (0.71) | DGKADNM1MAPTPAMALDH1A1 | |
| SCHEMBL7114491 | 0.95 | DGKA (0.71) | DGKADNM1MAPTPAMALDH1A1 | |
| SCHEMBL7113105 | 0.95 | DGKA (0.71) | DGKADNM1MAPTPAMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047577-A | Activator For Peroxygen Laundry Bleach | ETHYL CORPORATION (US) | 1991-09-10 | — | — | US | disclosed |