Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573169 | 0.90 | THRB (0.43) | THRBTDP1PDK2MEN1KMT2A | |
| SCHEMBL30519841 | 0.80 | THRB (0.70) | THRBTDP1PDK2AKR1B1FABP4 | |
| SCHEMBL68561 | 0.80 | THRB (0.70) | THRBTDP1PDK2AKR1B1FABP4 | |
| SCHEMBL11573163 | 0.76 | PDK2 (0.36) | PDK2MEN1KMT2AALDH1A1AKR1B1 | |
| SCHEMBL4023562 | 0.74 | THRB (0.64) | THRBTDP1PDK2MEN1KMT2A | |
| SCHEMBL8539410 | 0.73 | THRB (0.55) | THRBTDP1PDK2AKR1B1FABP4 | |
| SCHEMBL120476 | 0.73 | THRB (0.53) | THRBTDP1PDK2ALDH1A1AKR1B1 | |
| SCHEMBL15449183 | 0.69 | PDK2 (0.51) | THRBTDP1PDK2F2AKR1B1 | |
| SCHEMBL8827312 | 0.68 | PDK2 (0.50) | THRBTDP1PDK2ALDH1A1AKR1B1 | |
| SCHEMBL124841 | 0.68 | PDK2 (0.50) | THRBTDP1PDK2ALDH1A1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4135909-A | Salts of phosphonic acids | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |