Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.32 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573169 | 0.80 | THRB (0.43) | PDK2MEN1KMT2AACLYPSMB8 | |
| SCHEMBL11573153 | 0.76 | THRB (0.45) | PDK2MEN1KMT2AALDH1A1AKR1B1 | |
| Biphenyl SCHEMBL27373094 | 0.63 | SLC13A5 (0.55) | MEN1KMT2AALDH1A1CYP1A2HIF1A | |
| SCHEMBL10915746 | 0.61 | PDK2 (0.51) | PDK2ALDH1A1AKR1B1AKR1A1CYP1A2 | |
| SCHEMBL30519841 | 0.61 | THRB (0.70) | PDK2AKR1B1AKR1A1 | |
| SCHEMBL68561 | 0.61 | THRB (0.70) | PDK2AKR1B1AKR1A1 | |
| SCHEMBL9075500 | 0.61 | PDK2 (0.51) | PDK2AKR1B1AKR1A1 | |
| SCHEMBL8539410 | 0.59 | THRB (0.55) | PDK2AKR1B1AKR1A1 | |
| SCHEMBL4023562 | 0.58 | THRB (0.64) | PDK2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL2236854 | 0.58 | ALDH1A1 (0.65) | MEN1KMT2AACLYALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4135909-A | Salts of phosphonic acids | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |