Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571969 | 0.88 | ALDH1A1 (0.50) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL11571078 | 0.88 | POLB (0.44) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL11572479 | 0.88 | KDM4E (0.56) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL11572662 | 0.84 | KDM4E (0.49) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL11568718 | 0.83 | NPC1 (0.48) | MAPTPOLBNPC1RAB9AMTNR1A | |
| SCHEMBL11572282 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL11573154 | 0.83 | KDM4E (0.52) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL11571260 | 0.83 | KDM4E (0.52) | ALDH1A1TSHRHSD17B10MAPK10KDM4E | |
| SCHEMBL11570124 | 0.79 | KDM4E (0.46) | ALDH1A1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL11574421 | 0.77 | TDP1 (0.51) | ALDH1A1KDM4ELMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152114-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1979-05-01 | — | — | US | disclosed |
| US-4099909-A | POLYESTERS | CIBA-GEIGY AG (CH) | 1978-07-11 | — | — | US | disclosed |
| US-3963431-A | POLYESTER | CIBA-GEIGY AG (CH) | 1976-06-15 | — | — | US | disclosed |