Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570415 | 0.92 | ALDH1A1 (0.50) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL11574466 | 0.88 | MAPT (0.56) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL11569189 | 0.80 | MAPT (0.53) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL11572574 | 0.78 | MAPT (0.44) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL31083344 | 0.77 | MAPT (0.53) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL27496947 | 0.77 | MAOA (0.53) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL11569636 | 0.75 | MAPT (0.38) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL11569118 | 0.74 | SMN1; SMN2 (0.42) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL8390284 | 0.73 | ALDH1A1 (0.55) | MAPTMAPK1SMN1; SMN2PKMKMT2A | |
| SCHEMBL11131632 | 0.73 | POLB (0.63) | MAPTMAPK1SMN1; SMN2PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005288-A1 | Derivatives of 1-amino-fluoren-9-one and their use as herbicides | CHIMAC SOCIETE ANONYME (BE) | 1979-11-14 | — | — | EP | disclosed |