Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890300 | 0.90 | MEN1 (0.66) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL4831562 | 0.87 | NPC1 (0.73) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL11191641 | 0.86 | NPC1 (0.57) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL2681347 | 0.85 | NPC1 (0.80) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11574601 | 0.84 | NPC1 (0.56) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL10830768 | 0.84 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1TDP1 | |
| SCHEMBL11573279 | 0.84 | NPC1 (0.65) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL5897201 | 0.84 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL11575433 | 0.83 | ALDH1A1 (0.63) | NPC1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL5897795 | 0.81 | NPC1 (0.60) | NPC1RAB9AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |