Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | JAK2 | O60674 | 2/20 | 0.62 |
| ▸ | JAK1 | P23458 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | TYK2 | P29597 | 1/20 | 0.61 |
| ▸ | FADS1 | O60427 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573774 | 0.88 | SMN1; SMN2 (0.60) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 | |
| SCHEMBL11775702 | 0.88 | ALDH1A1 (0.58) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 | |
| SCHEMBL29929613 | 0.87 | JAK2 (0.78) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 | |
| SCHEMBL11575341 | 0.86 | ALDH1A1 (0.69) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 | |
| SCHEMBL11850758 | 0.86 | NPC1 (0.51) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 | |
| SCHEMBL11706082 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 | |
| SCHEMBL11177948 | 0.85 | ABL1 (0.65) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 | |
| SCHEMBL11574336 | 0.83 | NPC1 (0.59) | LMNAPOLBSMN1; SMN2PKMMEN1 | |
| SCHEMBL11591135 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 | |
| SCHEMBL16441856 | 0.82 | SMN1; SMN2 (0.72) | ALDH1A1LMNAPOLBSMN1; SMN2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |