Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14972696 | 0.87 | MEN1 (0.66) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL4409156 | 0.85 | KCNK3 (0.65) | KMT2AMEN1MAPTKCNK3KCNK9 | |
| SCHEMBL11127571 | 0.82 | NPC1 (0.67) | KMT2AMEN1MAPTLMNATP53 | |
| SCHEMBL16079860 | 0.82 | HDAC1 (0.69) | KMT2AMEN1MAPTLMNAKCNK3 | |
| SCHEMBL11202607 | 0.82 | KMT2A (0.62) | KMT2AMEN1MAPTKCNK3KCNK9 | |
| SCHEMBL16098188 | 0.82 | MEN1 (0.58) | KMT2AMEN1MAPTPTPN1POLB | |
| SCHEMBL18797052 | 0.81 | KMT2A (0.44) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL3530325 | 0.81 | KMT2A (0.69) | KMT2AMEN1MAPTKCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL11197738 | 0.81 | KMT2A (0.60) | KMT2AMEN1MAPTKCNK3KCNK9 | |
| SCHEMBL15388151 | 0.81 | KMT2A (0.67) | KMT2AMEN1MAPTLMNAKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080321-A | COLORFASTNESS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-03-21 | — | — | US | disclosed |