SCHEMBL4409156

SCHEMBL4409156

Nc1ccc(NC(=O)c2ccccc2)cc1N

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 1/20 0.65
KCNK9 Q9NPC2 1/20 0.65
NPC1 O15118 9/20 0.60
RAB9A P51151 9/20 0.60
PTPN1 P18031 2/20 0.59
KMT2A Q03164 4/20 0.58
SIRT1 Q96EB6 2/20 0.58
MEN1 O00255 2/20 0.58
KDM4E B2RXH2 1/20 0.58
POLB P06746 1/20 0.58
PLAU P00749 1/20 0.57
MAPT P10636 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
PKM P14618 1/20 0.57
ACE2 Q9BYF1 1/20 0.57
TP53 P04637 1/20 0.57
JAK2 O60674 1/20 0.56
JAK1 P23458 1/20 0.56
HDAC3 O15379 1/20 0.56
MAPK1 P28482 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11202607 0.86 KMT2A (0.62) KCNK3KCNK9NPC1RAB9APTPN1
SCHEMBL11325167 0.85 KMT2A (0.55) NPC1RAB9AKMT2AMEN1KDM4E
SCHEMBL4831562 0.85 NPC1 (0.73) KCNK3KCNK9NPC1RAB9APTPN1
SCHEMBL27474740 0.85 NPC1 (0.73) KCNK3KCNK9NPC1RAB9APTPN1
SCHEMBL11776642 0.85 KMT2A (0.69) KCNK3KCNK9NPC1RAB9APTPN1
Hydrochloric Acid SCHEMBL11197738 0.85 KMT2A (0.60) KCNK3KCNK9NPC1RAB9APTPN1
SCHEMBL11574792 0.85 KMT2A (0.62) KCNK3KCNK9NPC1RAB9APTPN1
SCHEMBL3241551 0.85 KMT2A (0.69) KCNK3KCNK9NPC1RAB9APTPN1
SCHEMBL29502995 0.85 KMT2A (0.69) KCNK3KCNK9NPC1RAB9APTPN1
SCHEMBL11322912 0.85 RAB9A (0.73) KCNK3KCNK9NPC1RAB9APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113444366-B Single layer polymer film and electronic device 杜邦电子公司 2025-05-27 CN disclosed
CN-111087617-B Low haze polymer film and electronic device 杜邦电子公司 2024-03-01 CN disclosed
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-02-15 US disclosed
CN-117510847-A Polyimide film and electronic device 杜邦电子公司 2024-02-06 CN disclosed
CN-111607225-B Polyimide film and electronic device 杜邦电子公司 2024-01-26 CN disclosed
CN-112480442-B Polyimide film and electronic device 杜邦电子公司 2024-01-23 CN disclosed
CN-116694073-A Polymer composition and coating solution 杜邦电子公司 2023-09-05 CN disclosed
CN-112824454-B Single layer polymer film and electronic device 杜邦电子公司 2023-07-04 CN disclosed
CN-115232471-A Polyimide film and electronic device 杜邦电子公司 2022-10-25 CN disclosed
CN-113493914-A Metal-clad polymer film and electronic device 杜邦电子公司 2021-10-12 CN disclosed
US-5089628-A Heat resistance, moisture resistance, low dielectric constants CENTRAL GLASS COMPANY, LIMITED (JP) 1992-02-18 US disclosed
US-5084345-A Laminates utilizing chemically etchable adhesives E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-28 US disclosed
EP-0032745-B1 ETHER IMIDES AND PROCESS FOR PRODUCING THE SAME Hitachi, Ltd. (JP) 1987-01-07 EP disclosed
US-4460783-A AMIDATION, CYCLIZATION, DEHYDRATION HITACHI, LTD. (JP) 1984-07-17 US disclosed
EP-0032745-A2 Ether imides and process for producing the same Hitachi, Ltd. (JP) 1981-07-29 EP disclosed
US-4138568-A NITRO-O-PHENYLENEDIAMINE, UREA, HALOBENZENE SOLVENT CIBA-GEIGY CORPORATION (US) 1979-02-06 US disclosed
US-4042611-A DYES AND PIGMENTS FOR PLASTICS, FIBERS, AND PAINTS HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-16 US disclosed
US-4008225-A Process for the manufacture of bis-azomethine metal complex colorants CIBA-GEIGY CORPORATION (US) 1977-02-15 US disclosed
US-3963708-A Bis-azomethine metal complex colorants from hydroxycoumarin derivatives or hydroxychromone derivatives CIBA-GEIGY CORPORATION (US) 1976-06-15 US disclosed
US-3939194-A Bis-2-azomethine pigments, process for their manufacture and their use CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM PUF60, PICALM, PARG KCNK3 3156/4885KCNK9 3000/4885NPC1 4317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.