Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28506022 | 0.91 | TDP1 (0.62) | TDP1MEN1KMT2AMAPTPOLB | |
| Fluoride SCHEMBL28506024 | 0.90 | TDP1 (0.60) | TDP1MEN1KMT2AMAPTPOLB | |
| SCHEMBL2419394 | 0.87 | PDE7A (0.56) | TDP1MEN1KMT2AMAPTPDE7A | |
| SCHEMBL11730953 | 0.84 | PDE7A (0.51) | TDP1MEN1KMT2AMAPTPOLB | |
| SCHEMBL19048971 | 0.81 | PDE7A (0.71) | TDP1MEN1KMT2AMAPTPOLB | |
| SCHEMBL10451352 | 0.80 | PDE7A (0.47) | TDP1MEN1KMT2AMAPTPOLB | |
| SCHEMBL11574501 | 0.80 | PDE7A (0.56) | TDP1MEN1KMT2AMAPTPDE7A | |
| SCHEMBL20727298 | 0.80 | MAPK1 (0.51) | MEN1KMT2AMAPTALDH1A1ALOX15 | |
| SCHEMBL15155301 | 0.80 | PDE7A (0.60) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1369423 | 0.80 | CES2 (0.53) | TDP1MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496192-B | Preparation method of 4-phenylthio-1, 2-phenylenediamine | 山东国邦药业有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116496192-A | Preparation method of 4-phenylthio-1, 2-phenylenediamine | 山东国邦药业有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-116063212-B | Preparation method of 4-phenylthio-1, 2-phenylenediamine | 山东国邦药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-116063212-A | Preparation method of 4-phenylthio-1, 2-phenylenediamine | 山东国邦药业有限公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-114716354-B | Synthesis method of fenbendazole intermediate 2-nitro-4-thiophenylaniline | 山东国邦药业有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114716354-A | Synthesis method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-111349032-B | Preparation method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-111349032-A | Preparation method of fenbendazole intermediate 2-nitro-4-thiophenyl aniline | 山东国邦药业有限公司 | 2020-06-30 | — | — | CN | disclosed |
| US-4127670-A | ANTHELMINTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-28 | — | — | US | disclosed |