Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909396 | 0.96 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2912069 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL11575861 | 0.83 | ALDH1A1 (0.49) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL7139135 | 0.83 | MAPT (0.46) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2911518 | 0.83 | ALDH1A1 (0.60) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL18407133 | 0.82 | MAPT (0.45) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL2911528 | 0.80 | KDM4E (0.60) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL11232605 | 0.80 | ALDH1A1 (0.66) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL8995821 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL295936 | 0.79 | KMT2A (0.83) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |