SCHEMBL2909396

SCHEMBL2909396

CC(=O)CC(=O)Nc1cc(C)c(NC(=O)CC(C)=O)cc1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
MAPT P10636 2/20 0.53
ALDH1A1 P00352 7/20 0.47
HTT P42858 2/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
PKM P14618 1/20 0.45
KDM4E B2RXH2 4/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
POLB P06746 2/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11575236 0.96 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL2912069 0.89 ALDH1A1 (0.48) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL11575861 0.87 ALDH1A1 (0.49) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL2911518 0.86 ALDH1A1 (0.60) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL7139135 0.86 MAPT (0.46) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL2911528 0.83 KDM4E (0.60) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL8995821 0.83 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL1577190 0.83 HDAC3 (0.62) MEN1KMT2AALDH1A1HTTLMNA
SCHEMBL295936 0.83 KMT2A (0.83) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL3237854 0.82 BRPF1 (0.46) MEN1KMT2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756486-B1 LAKED DISAZO YELLOW PIGMENTS HAVING DESIRABLE GREEN SHADE, HEAT STABILITY, GOOD STRENGTH, BLEED RESISTANCE, MIGRATION RESISTANCE, AND LOW OR NO TOXICITY ENGELHARD CORPORATION 2004-06-29 US claimed
EP-0581245-B1 Water-insoluble azo colouring agents CLARIANT GMBH (DE) 1998-12-23 EP claimed
EP-0581245-A1 Water-insoluble azo colouring agents HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-02 EP claimed
US-9234256-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2016-01-12 US disclosed
US-9234256-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2016-01-12 US disclosed
US-8652335-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2014-02-18 US disclosed
US-8652335-B2 Scavenger supports and the use thereof in a process for the extraction of metals JOHNSON MATTHEY FINLAND OY (FI) 2014-02-18 US disclosed
US-20120211439-A1 SCAVENGER SUPPORTS AND THE USE THEREOF IN A PROCESS FOR THE EXTRACTION OF METALS JOHNSON MATTHEY FINLAND OY (FI) 2012-08-23 US disclosed
US-20120211439-A1 SCAVENGER SUPPORTS AND THE USE THEREOF IN A PROCESS FOR THE EXTRACTION OF METALS JOHNSON MATTHEY FINLAND OY (FI) 2012-08-23 US disclosed
US-8177861-B2 AZO pigment, pigment dispersion containing the AZO pigment, and coloring composition FUJIFILM CORPORATION (JP) 2012-05-15 US disclosed
US-20110021764-A1 AZO PIGMENT, PIGMENT DISPERSION CONTAINING THE AZO PIGMENT, AND COLORING COMPOSITION FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
US-4540775-A ORANGE PIGMENT FOR POLYMERS SANDOZ LTD. (CH) 1985-09-10 US disclosed
EP-0025164-B1 DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-13 EP disclosed
EP-0025164-A1 Disazo compounds, process for their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1981-03-18 EP disclosed
US-4221709-A Azo pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1980-09-09 US disclosed
US-4065449-A Tetrachloro substituted disazo pigments CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4062838-A LACQUERS, PRINTING INKS, YELLOW TO ORANGE CIBA-GEIGY CORPORATION (US) 1977-12-13 US disclosed
US-4003886-A Tetracarboxylic acid ester substituted disazo pigments CIBA-GEIGY AG (CH) 1977-01-18 US disclosed
US-3978038-A POLYAMIDES, POLYESTERS, POLYURETHANES CIBA-GEIGY CORPORATION (US) 1976-08-31 US disclosed
US-3956266-A DISAZO DYES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed