Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 5/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 3/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.60 |
| ▸ | DRD1 | P21728 | 3/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423784 | 0.91 | SETD7 (0.53) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11574345 | 0.91 | SETD7 (0.53) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11575971 | 0.90 | SETD7 (0.76) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11573964 | 0.90 | KCNH2 (0.76) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11423683 | 0.89 | SETD7 (0.51) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11160059 | 0.89 | SETD7 (0.51) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| Fumaric Acid SCHEMBL11596650 | 0.81 | HTT (0.80) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| Maleic Acid SCHEMBL11596646 | 0.81 | HTT (0.80) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11161207 | 0.77 | CYP2D6 (0.39) | SETD7CHRM2HTR1AADRA2ACHRM1 | |
| Pimethixene SCHEMBL29433731 | 0.76 | SETD7 (1.00) | SETD7CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086350-A | FLUORO, CHLORO AND CYANO SUBSTITUTED 4-(9-XANTHENYLIDENE, 9-THIOXANTHENYLIDENE OR 11(6H)-DIBENZO(B,E)OXEPINYLIDENE)-1-METHYL-PIPERIDINES | SMITHKLINE CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |