Pimethixene

Pimethixene

SCHEMBL29433731

CN1CCC(=C2c3ccccc3Sc3ccccc32)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SETD7 Q8WTS6 5/20 1.00
▸ CHRM2 P08172 5/20 1.00
▸ CHRM1 P11229 5/20 1.00
▸ ADRA1A P35348 5/20 1.00
▸ KCNH2 Q12809 5/20 1.00
▸ ADRA2A P08913 4/20 1.00
▸ DRD1 P21728 4/20 1.00
▸ DRD3 P35462 4/20 1.00
▸ HTR1A P08908 4/20 1.00
▸ SLC6A2 P23975 3/20 1.00
▸ SLC6A4 P31645 3/20 1.00
▸ SLC6A3 Q01959 3/20 1.00
▸ CYP2D6 P10635 3/20 1.00
▸ CYP2C19 P33261 3/20 1.00
▸ TBXA2R P21731 2/20 1.00
▸ OPRM1 P35372 2/20 1.00
▸ ADORA3 P0DMS8 1/20 1.00
▸ HTT P42858 2/20 0.76
▸ CYP3A4 P08684 2/20 0.76
▸ HTR2A P28223 4/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pimethixene SCHEMBL301596 1.00 SETD7 (1.00) SETD7CHRM2CHRM1ADRA1AKCNH2
Pimethixene SCHEMBL301226 0.87 HTT (1.00) SETD7CHRM2CHRM1ADRA1AKCNH2
SCHEMBL11573964 0.87 KCNH2 (0.76) SETD7CHRM2CHRM1ADRA1AKCNH2
Pimethixene SCHEMBL301225 0.87 HTT (1.00) SETD7CHRM2CHRM1ADRA1AKCNH2
SCHEMBL11575971 0.87 SETD7 (0.76) SETD7CHRM2CHRM1ADRA1AKCNH2
SCHEMBL11573081 0.87 SETD7 (0.76) SETD7CHRM2CHRM1ADRA1AKCNH2
SCHEMBL11432245 0.87 HTR1A (0.76) SETD7CHRM2CHRM1ADRA1AKCNH2
SCHEMBL11574284 0.87 SETD7 (0.76) SETD7CHRM2CHRM1ADRA1AKCNH2
SCHEMBL11600806 0.85 DRD3 (0.73) SETD7CHRM2CHRM1ADRA1AKCNH2
SCHEMBL11431794 0.85 SETD7 (0.72) SETD7CHRM2CHRM1ADRA1AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 — — WO claimed
US-20250041208-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2025-02-06 — — US claimed
CN-119082349-A Primer pair, kit and method for identifying Stemona sessilifolia traditional Chinese medicine raw plants, medicinal materials or decoction pieces with different origins 广东一方制药有限公司 2024-12-06 — — CN claimed
EP-4444277-A1 NEW INJECTABLE COMBINATION FORMULATION Nanexa AB (SE) 2024-10-16 — — EP claimed
CN-114457143-B Method for constructing CNV detection library and CNV detection method 苏州贝康医疗器械有限公司 2024-07-09 — — CN claimed
CN-115651974-B Artificial simulated cfDNA standard, preparation method and application thereof 纳昂达(南京)生物科技有限公司 2024-03-08 — — CN claimed
WO-2023105227-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2023-06-15 — — WO claimed
CN-115651974-A Artificial simulation cfDNA standard substance and preparation method and application thereof 纳昂达(南京)生物科技有限公司 2023-01-31 — — CN claimed
CN-113281117-B Preparation method of synthetic surface 中国空间技术研究院 2022-12-06 — — CN claimed
CN-114457143-A Method for constructing CNV detection library and CNV detection method 苏州贝康医疗器械有限公司 2022-05-10 — — CN claimed
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 — — WO disclosed
US-12624113-B2 Anti-human CCR1 monoclonal antibody KYOWA KIRIN CO., LTD. (JP) 2026-05-12 — — US disclosed
US-12606615-B2 Anti-FGF23 antibody or antibody fragment thereof KYOWA KIRIN CO., LTD. (JP) 2026-04-21 — — US disclosed
US-12601006-B2 Targeted, long-read nucleic acid sequencing for the determination of cytosine modifications LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (CH) 2026-04-14 — — US disclosed
US-20260092110-A1 ANTIBODY WHICH BINDS TO MYELIN OLIGODENDROCYTE GLYCOPROTEIN KYOWA KIRIN CO., LTD. (JP) 2026-04-02 — — US disclosed
CN-114005490-B Circulating tumor DNA fusion detection method based on second-generation sequencing technology 北京优迅医疗器械有限公司 2022-04-22 — — CN disclosed
CN-114277120-A Medicine for treating alpha-thalassemia and diagnostic kit 深圳市坪山区人民医院 2022-04-05 — — CN disclosed
EP-3971293-A1 BISPECIFIC ANTIBODY CAPABLE OF BINDING TO CD40 AND GPC3 Kyowa Kirin Co., Ltd. (JP) 2022-03-23 — — EP disclosed
EP-3970743-A1 BISPECIFIC ANTIBODY BINDING TO CD40 AND FAP Kyowa Kirin Co., Ltd. (JP) 2022-03-23 — — EP disclosed
CN-114005490-A Circulating tumor DNA fusion detection method based on second-generation sequencing technology 北京优迅医疗器械有限公司 2022-02-01 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12601006-B2 Targeted, long-read nucleic acid sequencing for the determination of cytosine modifications TET1, TET3, TET2 SETD7 683/4885CHRM2 4789/4885CHRM1 4706/4885
US-12606615-B2 Anti-FGF23 antibody or antibody fragment thereof FGF23, IGLV6-57, FCGR3B SETD7 869/4885CHRM2 2658/4885CHRM1 3100/4885
US-12624113-B2 Anti-human CCR1 monoclonal antibody CCR1, CCR4, CCRL2 SETD7 433/4885CHRM2 1451/4885CHRM1 1648/4885
US-20260092110-A1 ANTIBODY WHICH BINDS TO MYELIN OLIGODENDROCYTE GLYCOPROTEIN MAG, IGSF11, GMFG SETD7 1584/4885CHRM2 1504/4885CHRM1 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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