Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 5/20 | 0.58 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | DRD1 | P21728 | 4/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | HTR2B | P41595 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11572834 | 0.91 | SETD7 (0.56) | SETD7DRD2KCNH2CHRM2HTR1A | |
| SCHEMBL13870476 | 0.90 | SETD7 (0.58) | SETD7DRD2KCNH2CHRM2HTR1A | |
| SCHEMBL11576524 | 0.89 | SETD7 (0.56) | SETD7DRD2KCNH2CHRM2HTR1A | |
| SCHEMBL11600017 | 0.87 | SETD7 (0.71) | SETD7DRD2KCNH2CHRM2HTR1A | |
| Clopipazan SCHEMBL1816896 | 0.83 | SETD7 (0.76) | SETD7DRD2KCNH2CHRM2HTR1A | |
| SCHEMBL3138857 | 0.81 | SETD7 (0.53) | SETD7KCNH2HRH1TBXA2RHTT | |
| SCHEMBL3131282 | 0.77 | SETD7 (0.57) | SETD7DRD2KCNH2CHRM2HTR1A | |
| SCHEMBL13712944 | 0.77 | SETD7 (0.57) | SETD7DRD2KCNH2CHRM2HTR1A | |
| Clopipazan SCHEMBL120732 | 0.76 | SETD7 (0.64) | SETD7DRD2KCNH2CHRM2HTR1A | |
| SCHEMBL3134805 | 0.76 | SETD7 (0.47) | SETD7KCNH2DRD3HRH1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086350-A | FLUORO, CHLORO AND CYANO SUBSTITUTED 4-(9-XANTHENYLIDENE, 9-THIOXANTHENYLIDENE OR 11(6H)-DIBENZO(B,E)OXEPINYLIDENE)-1-METHYL-PIPERIDINES | SMITHKLINE CORPORATION (US) | 1978-04-25 | — | — | US | claimed |
| US-4086350-A | FLUORO, CHLORO AND CYANO SUBSTITUTED 4-(9-XANTHENYLIDENE, 9-THIOXANTHENYLIDENE OR 11(6H)-DIBENZO(B,E)OXEPINYLIDENE)-1-METHYL-PIPERIDINES | SMITHKLINE CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |