Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11280547 | 0.81 | MCL1 (0.39) | KDM4EATMALDH1A1TSHRLMNA | |
| SCHEMBL11281640 | 0.78 | POLB (0.42) | KDM4ETNKS2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11276789 | 0.74 | CA12 (0.38) | MCL1 | |
| SCHEMBL11287721 | 0.72 | TNKS2 (0.44) | KDM4ETNKS2CYP1A2CYP2C19MCL1 | |
| SCHEMBL11277267 | 0.71 | DRD2 (0.49) | ADRB2 | |
| SCHEMBL11285765 | 0.71 | PDE3B (0.34) | KDM4EATMALDH1A1TSHRLMNA | |
| SCHEMBL10927018 | 0.70 | KDM4E (0.44) | KDM4ECYP1A2CYP2C19ALDH1A1TSHR | |
| SCHEMBL11273854 | 0.70 | CTSV (0.33) | KDM4EATMALDH1A1TSHRLMNA | |
| SCHEMBL11280760 | 0.68 | KDM4E (0.38) | KDM4EATMALDH1A1TSHRLMNA | |
| SCHEMBL7318670 | 0.68 | HSD17B10 (0.41) | KDM4EATMCYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003771-A1 | Carbostyrile derivatives, their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |