Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577014 | 0.88 | ALDH1A1 (0.35) | ALDH1A1TSHRHTTKDM5AMAPT | |
| SCHEMBL11642976 | 0.77 | NPC1 (0.48) | ALDH1A1GFERKDM4EHPGDHSD17B10 | |
| SCHEMBL9808943 | 0.76 | GAA (0.48) | ALDH1A1HTTMAPTMEN1GFER | |
| SCHEMBL11780099 | 0.75 | HDAC1 (0.35) | ALDH1A1MAPTMEN1GFERKMT2A | |
| SCHEMBL11574641 | 0.75 | HDAC2 (0.33) | ALDH1A1HDAC1 | |
| SCHEMBL9808892 | 0.75 | ALOX15 (0.36) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL11644479 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1TSHRHTTMAPTMEN1 | |
| SCHEMBL11646651 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HTTMAPTKDM4EGAA | |
| SCHEMBL11638524 | 0.73 | MDM4 (0.43) | ALDH1A1HTTMAPTMEN1KMT2A | |
| SCHEMBL11647190 | 0.72 | GAA (0.42) | ALDH1A1HTTMAPTMEN1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127670-A | ANTHELMINTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-28 | — | — | US | disclosed |