Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30309662 | 0.84 | CA1 (0.61) | MEP1BALDH1A1KMT2APDK1PDK2 | |
| SCHEMBL16735334 | 0.84 | CA1 (0.61) | MEP1BALDH1A1KMT2APDK1PDK2 | |
| SCHEMBL20202276 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KMT2APDK1PDK2PDK3 | |
| SCHEMBL11963336 | 0.81 | MEP1B (0.62) | MEP1BALDH1A1KMT2AHPGDPOLB | |
| SCHEMBL20743729 | 0.80 | ALDH1A1 (0.49) | MEP1BALDH1A1KMT2APDK1PDK2 | |
| SCHEMBL30309627 | 0.80 | ALDH1A1 (0.49) | MEP1BALDH1A1KMT2APDK1PDK2 | |
| SCHEMBL9307678 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KMT2APDK1PDK2PDK3 | |
| SCHEMBL18995904 | 0.77 | ALDH1A1 (0.59) | ALDH1A1KMT2APDK1PDK2PDK3 | |
| SCHEMBL31717190 | 0.76 | FEN1 (0.54) | ALDH1A1MAPTL3MBTL1TDP1TP53 | |
| SCHEMBL21510335 | 0.75 | MEP1B (0.52) | MEP1BALDH1A1KMT2AHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190321313-A1 | BENZENESULFONAMIDE DERIVATIVES AND METHOD FOR TREATING CANCER | Gongwin Biopharm Holdings Co., Ltd. | 2019-10-24 | — | — | US | disclosed |
| US-4113463-A | BENZENESULFONAMIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-09-12 | — | — | US | disclosed |
| US-4070176-A | WITH A BENZENESULFONAMIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190321313-A1 | BENZENESULFONAMIDE DERIVATIVES AND METHOD FOR TREATING CANCER | ARSA, ABCB1, ABCG2 | MEP1B 3157/4885ALDH1A1 689/4885KMT2A 2364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.