SCHEMBL11575652

SCHEMBL11575652

Nc1cc(Cl)c(S(=O)(=O)O)c(Br)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
TSHR P16473 4/20 0.44
CYP3A4 P08684 3/20 0.44
HSD17B10 Q99714 3/20 0.44
THRB P10828 2/20 0.44
CASP1 P29466 2/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
RECQL P46063 1/20 0.44
CA1 P00915 9/20 0.39
CA2 P00918 9/20 0.39
CA9 Q16790 7/20 0.39
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.36
TDP1 Q9NUW8 3/20 0.33
CA12 O43570 2/20 0.33
CA3 P07451 2/20 0.33
CA4 P22748 2/20 0.33
CA6 P23280 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL342035 0.86 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4HSD17B10THRB
SCHEMBL11522707 0.80 NMT1 (0.41) TSHRCYP3A4CA1CA2CA9
SCHEMBL21589348 0.77 ALDH1A1 (0.44) ALDH1A1TSHRCYP3A4HSD17B10THRB
SCHEMBL29157632 0.77 NMT1 (0.40) ALDH1A1CYP3A4CA1CA2CA9
SCHEMBL4381560 0.74 CA1 (0.48) ALDH1A1TSHRCYP3A4HSD17B10THRB
SCHEMBL27916251 0.73 CA1 (0.39) ALDH1A1TSHRHSD17B10CASP1CA1
SCHEMBL11524504 0.73 NMT1 (0.41) ALDH1A1TSHRCYP3A4HSD17B10THRB
SCHEMBL1913756 0.72 GAA (0.50) ALDH1A1TSHRCA1CA2CA9
SCHEMBL27916306 0.72 CA1 (0.38) ALDH1A1TSHRHSD17B10CA1CA2
Fluoride SCHEMBL27937404 0.70 L3MBTL1 (0.44) ALDH1A1TSHRCYP3A4HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54072258-A None JP disclosed
JP-S5472258-A FLAME-RETARDANT POLYAMIDE RESIN COMPOSITION TORAY IND INC 1979-06-09 JP disclosed