Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912176 | 0.93 | MEN1 (0.54) | MEN1KMT2AALDH1A1POLBTDP1 | |
| SCHEMBL12720508 | 0.84 | MEN1 (0.80) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL11576411 | 0.84 | CYP3A4 (0.54) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL10427609 | 0.80 | MEN1 (0.53) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL9180503 | 0.77 | HPGD (0.68) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL31590796 | 0.77 | HPGD (0.68) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL54924 | 0.77 | MEN1 (0.80) | MEN1KMT2AALDH1A1POLBTDP1 | |
| SCHEMBL11222525 | 0.77 | MEN1 (0.51) | MEN1KMT2AALDH1A1POLBTDP1 | |
| SCHEMBL2914539 | 0.77 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1POLBTDP1 | |
| SCHEMBL7133200 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |