Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846934 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL44699 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2POLBAKR1B1MAPT | |
| SCHEMBL9485968 | 0.74 | GABRA1 (0.41) | GABRA1GABRB2POLBAKR1B1MAPT | |
| SCHEMBL1624908 | 0.72 | TDP1 (0.45) | GABRA1GABRB2POLBCYP3A4CNR2 | |
| SCHEMBL11304232 | 0.72 | CYP2C19 (0.39) | GABRA1GABRB2POLBCYP3A4CYP1A2 | |
| SCHEMBL11306575 | 0.70 | GABRA1 (0.54) | GABRA1GABRB2AKR1B1MAPTKMT2A | |
| SCHEMBL6278626 | 0.69 | GABRA1 (0.41) | GABRA1GABRB2POLBAKR1B1MAPT | |
| SCHEMBL5481769 | 0.68 | GABRA1 (0.38) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL1276109 | 0.67 | GABRA1 (0.36) | GABRA1GABRB2POLBMAPTKMT2A | |
| SCHEMBL8665741 | 0.67 | LMNA (0.41) | GABRA1GABRB2POLBMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170711-A | FLAME RETARDANTS FOR POLYESTERS, POLYCARBONATES, AND POLYURETHANES | GENERAL ELECTRIC COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4170711-A | FLAME RETARDANTS FOR POLYESTERS, POLYCARBONATES, AND POLYURETHANES | GENERAL ELECTRIC COMPANY (US) | 1979-10-09 | — | — | US | disclosed |