SCHEMBL11575857

SCHEMBL11575857

COc1cc(CCCCCCCCCCCCC(N)=O)ccc1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.66
CYP1A2 P05177 2/20 0.65
CYP3A4 P08684 2/20 0.65
CYP2C9 P11712 2/20 0.65
CYP2C19 P33261 2/20 0.65
CYP2C8 P10632 1/20 0.65
CYP2B6 P20813 1/20 0.65
OR51E2 Q9H255 1/20 0.62
TAAR1 Q96RJ0 2/20 0.62
TSHR P16473 1/20 0.62
MAPK1 P28482 1/20 0.62
LMNA P02545 1/20 0.60
GLA P06280 1/20 0.60
MTNR1A P48039 1/20 0.60
MTNR1B P49286 1/20 0.60
TRPV1 Q8NER1 1/20 0.56
ALDH1A1 P00352 1/20 0.55
CYP2D6 P10635 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28378162 1.00 ALOX5 (0.66) ALOX5CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2683415 1.00 ALOX5 (0.66) ALOX5CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL906528 0.98 ALOX5 (0.67) ALOX5CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL5723843 0.94 ALOX5 (0.66) ALOX5CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL4155154 0.92 HTR1A (0.64) ALOX5CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL5724212 0.89 ALOX5 (0.72) ALOX5CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL5192275 0.89 KDM4E (0.57) ALOX5
SCHEMBL4086224 0.88 ALOX5 (0.70) ALOX5CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2221405 0.88 KDM4E (0.59) ALOX5ALDH1A1
SCHEMBL5353374 0.87 HTR1A (0.61) ALOX5CYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-53132534-A None JP disclosed
JP-S53132534-A VANILLYLACYLAMIDE AND ANTIOXIDANT CONTAINING THE SAME EISAI CO LTD 1978-11-18 JP disclosed