Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784133 | 0.85 | MAOA (0.62) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL11634005 | 0.81 | NPC1 (0.41) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Xanthone SCHEMBL29358061 | 0.78 | MAOA (1.00) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Xanthone SCHEMBL41161 | 0.78 | MAOA (1.00) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Xanthone SCHEMBL29398266 | 0.78 | MAOA (1.00) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Xanthone SCHEMBL2354794 | 0.78 | MAOA (1.00) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12608739 | 0.77 | MAOA (0.72) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21666688 | 0.76 | MAOA (0.78) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Xanthone SCHEMBL11399893 | 0.75 | MAOA (0.95) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| Xanthone SCHEMBL5376736 | 0.75 | MAOA (0.95) | MAOAMAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086350-A | FLUORO, CHLORO AND CYANO SUBSTITUTED 4-(9-XANTHENYLIDENE, 9-THIOXANTHENYLIDENE OR 11(6H)-DIBENZO(B,E)OXEPINYLIDENE)-1-METHYL-PIPERIDINES | SMITHKLINE CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |