SCHEMBL11575979

SCHEMBL11575979

COCCCN(CCCl)S(=O)(=O)Cl

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.40
GSTO1 P78417 1/20 0.33
ALDH1A1 P00352 1/20 0.31
GRIN1 Q05586 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11570717 0.88 VCAM1 (0.35)
SCHEMBL11570430 0.81 ALDH1A1 (0.36) ALDH1A1GRIN1TSHR
SCHEMBL11569851 0.80 TSHR (0.39) ALDH1A1TSHR
SCHEMBL7673928 0.79 VCAM1 (0.38) MAPK1TSHR
SCHEMBL11571831 0.78 EGFR (0.37) ALDH1A1TSHR
SCHEMBL11569934 0.78 MEN1 (0.42) MAPK1TSHR
SCHEMBL11571089 0.74 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL11571274 0.74 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL11571290 0.74 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL11569463 0.74 KMT2A (0.46) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4173580-A Production of β-haloalkylaminosulfonyl halides BASF AKTIENGESELLSCHAFT (DE) 1979-11-06 US claimed
US-4173580-A Production of β-haloalkylaminosulfonyl halides BASF AKTIENGESELLSCHAFT (DE) 1979-11-06 US disclosed
US-4014931-A FROM AZIRIDINE AND SULFURYL HALIDE BASF AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed