Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | TNFRSF1A | P19438 | 5/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.52 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539495 | 0.76 | ABCG2 (0.68) | ABCG2TNFRSF1AABCB1TUBB1POLB | |
| SCHEMBL18480640 | 0.74 | ABCG2 (0.66) | ABCG2TNFRSF1AABCB1TUBB1POLB | |
| Baxitozine SCHEMBL9321098 | 0.74 | ABCG2 (0.66) | ALDH1A1ABCG2TNFRSF1AABCB1TUBB1 | |
| Baxitozine SCHEMBL6859777 | 0.74 | ABCG2 (0.66) | ALDH1A1ABCG2TNFRSF1AABCB1TUBB1 | |
| SCHEMBL14800858 | 0.73 | ABCG2 (0.84) | ALDH1A1ABCG2TNFRSF1AABCB1TUBB1 | |
| SCHEMBL14820484 | 0.73 | ABCG2 (0.84) | ALDH1A1ABCG2TNFRSF1AABCB1TUBB1 | |
| SCHEMBL374153 | 0.72 | ABCG2 (0.62) | ABCG2TNFRSF1AABCB1TUBB1POLB | |
| SCHEMBL8590732 | 0.72 | POLB (0.63) | LMNAABCG2TNFRSF1AABCB1TUBB1 | |
| SCHEMBL805335 | 0.72 | MAPT (0.69) | LMNAALDH1A1MAPTABCG2TNFRSF1A | |
| SCHEMBL783240 | 0.72 | MAPT (0.69) | LMNAALDH1A1MAPTABCG2TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2267 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622640-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF | Brightseed, Inc. (US) | 2025-10-01 | — | — | EP | claimed |
| US-20250281451-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF | BRIGHTSEED, INC. | 2025-09-11 | — | — | US | claimed |
| US-20240238250-A1 | METHOD OF USING PIROMELATINE FOR TREATING PARASOMNIAS ASSOCIATED WITH LOSS OF REM SLEEP ATONIA | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2024-07-18 | — | — | US | claimed |
| WO-2024150170-A1 | PIROMELATINE FOR TREATING PARASOMNIAS ASSOCIATED WITH LOSS OF REM SLEEP ATONIA | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2024-07-18 | — | — | WO | claimed |
| WO-2024112947-A1 | COMPOSITIONS AND METHODS FOR MODULATING SLEEP AND USES THEREOF | BRIGHTSEED, INC. (US) | 2024-05-30 | — | — | WO | claimed |
| US-20190275048-A1 | METHOD OF TREATING INSOMNIA | ROSENBERG LEON I (US) | 2019-09-12 | — | — | US | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-8735383-B2 | Glycine transporter-1 inhibitors | AMGEN INC. (US) | 2014-05-27 | — | — | US | claimed |
| US-20120195985-A1 | GLYCINE TRANSPORTER-1 INHIBITORS | AMGEN INC. (US) | 2012-08-02 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| EP-1599199-A2 | METHODS FOR TREATING JOINT PAIN OR IMPROVING SLEEP USING AN ESTROGEN AGONIST/ANTAGONIST | Pfizer Products Inc. (US) | 2005-11-30 | — | — | EP | claimed |
| US-20040152713-A1 | Methods for treating joint pain or improving sleep using an estrogen agonist/antagonist | PFIZER INC. | 2004-08-05 | — | — | US | claimed |
| WO-2004064832-A2 | METHODS FOR TREATING JOINT PAIN OR IMPROVING SLEEP USING AN ESTROGEN AGONIST/ANTAGONIST | PFIZER PRODUCTS INC. (US) | 2004-08-05 | — | — | WO | claimed |
| JP-2000511885-A | — | — | 2000-09-12 | — | — | JP | claimed |
| EP-0900086-A4 | ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE | MERCK & CO INC (US) | 2000-01-12 | — | — | EP | claimed |
| EP-0900086-A1 | ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE | Merck & Co., Inc. (US) | 1999-03-10 | — | — | EP | claimed |
| WO-1997041879-A1 | ENHANCEMENT OF SLEEP WITH A GROWTH HORMONE SECRETAGOGUE | MERCK & CO., INC. (US) | 1997-11-13 | — | — | WO | claimed |