Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573909 | 0.88 | NPC1 (0.48) | HTR6ALDH1A1PKMMAPTLMNA | |
| SCHEMBL11578071 | 0.86 | HTR6 (0.44) | HTR6ALDH1A1PKMMAPTLMNA | |
| SCHEMBL11642077 | 0.76 | NPC1 (0.63) | HTR6ALDH1A1PKMMAPTLMNA | |
| SCHEMBL11783205 | 0.76 | NPC1 (0.43) | HTR6ALDH1A1PKMMAPTLMNA | |
| SCHEMBL950448 | 0.76 | HTR6 (0.74) | HTR6ALDH1A1PKMMAPTLMNA | |
| SCHEMBL30166976 | 0.76 | HTR6 (0.74) | HTR6ALDH1A1PKMMAPTLMNA | |
| SCHEMBL9489735 | 0.74 | ALDH1A1 (0.61) | HTR6ALDH1A1PKMMAPTLMNA | |
| SCHEMBL11643502 | 0.74 | CA12 (0.59) | MAPTSMN1; SMN2CYP2C9TSHRHPGD | |
| SCHEMBL11647034 | 0.74 | ALDH1A1 (0.47) | ALDH1A1PKMMAPTLMNAPOLB | |
| SCHEMBL7559625 | 0.73 | HTR6 (0.66) | HTR6ALDH1A1PKMMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127670-A | ANTHELMINTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-28 | — | — | US | disclosed |