Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | FABP2 | P12104 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918478 | 0.96 | ADORA3 (0.65) | ADORA3PPARAMEN1KMT2ACYP2C19 | |
| SCHEMBL12918477 | 0.94 | ADORA3 (0.64) | ADORA3PPARAMEN1KMT2ACYP2C19 | |
| SCHEMBL12918480 | 0.93 | PPARA (0.68) | ADORA3PPARAMEN1KMT2ACYP2C19 | |
| Clinofibrate SCHEMBL20339978 | 0.82 | ADORA3 (1.00) | ADORA3PPARAMEN1KMT2ACYP2C19 | |
| Clinofibrate SCHEMBL31290 | 0.82 | ADORA3 (1.00) | ADORA3PPARAMEN1KMT2ACYP2C19 | |
| Clinofibrate SCHEMBL3955329 | 0.82 | ADORA3 (1.00) | ADORA3PPARAMEN1KMT2ACYP2C19 | |
| Clinofibrate SCHEMBL11223466 | 0.81 | ADORA3 (0.97) | ADORA3PPARAMEN1KMT2ACYP2C19 | |
| SCHEMBL11576866 | 0.81 | ADORA3 (0.62) | ADORA3PPARACYP1A2CYP3A4PPARG | |
| SCHEMBL15869211 | 0.80 | SLC6A4 (0.61) | ADORA3MAPTLMNAESR1ESR2 | |
| SCHEMBL12918479 | 0.79 | ADORA3 (0.92) | ADORA3PPARAMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092324-A | ANTIARTERIOSCLEROSIS AGENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-05-30 | — | — | US | disclosed |
| US-4008265-A | ANTIARTERIOSCLEROSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-02-15 | — | — | US | disclosed |