Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503602 | 0.94 | MAPT (0.56) | TSHRMAPTKMT2AKCNH2EPHX1 | |
| SCHEMBL9503608 | 0.87 | BCL9 (0.58) | TSHRMAPTKMT2AKCNH2KCNJ1 | |
| SCHEMBL10358149 | 0.84 | ALDH1A1 (0.50) | TSHRMAPTKMT2AKCNH2EPHX1 | |
| SCHEMBL153580 | 0.84 | MAPT (0.61) | TSHRMAPTKMT2AKCNH2HDAC3 | |
| SCHEMBL153108 | 0.84 | MAPT (0.61) | TSHRMAPTKMT2AKCNH2HDAC3 | |
| SCHEMBL1400171 | 0.84 | MAPT (0.61) | TSHRMAPTKMT2AKCNH2HDAC3 | |
| SCHEMBL154515 | 0.84 | MAPT (0.61) | TSHRMAPTKMT2AKCNH2HDAC3 | |
| SCHEMBL2945405 | 0.84 | MAPT (0.61) | TSHRMAPTKMT2AKCNH2HDAC3 | |
| SCHEMBL2944805 | 0.84 | MAPT (0.61) | TSHRMAPTKMT2AKCNH2HDAC3 | |
| SCHEMBL2952790 | 0.84 | MAPT (0.61) | TSHRMAPTKMT2AKCNH2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097665-A | Diacylnucleosides and process for preparing the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-27 | — | — | US | disclosed |